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Pulmonary Intravascular Macrophages (PIMs) are specialized immune cells found within the blood vessels of the lungs. They play a crucial role in the body's defense, actively identifying and engulfing pathogens, cellular debris, and foreign substances circulating through the pulmonary vasculature. This vital phagocytic activity helps maintain lung health and protects against systemic infection, making them key players in respiratory immunology and disease response.