The Histamine H3 Receptor
The Histamine H3 Receptor is a G protein-coupled receptor predominantly found in the central nervous system, where it acts as an autoreceptor and heteroreceptor to modulate the release of histamine and other neurotransmitters. It plays a crucial role in regulating various physiological processes, including the sleep-wake cycle, cognition, and arousal, making it a significant target for pharmacological research into neurological disorders and cognitive enhancement.